Observational studies have recently received significant attention from the machine learning community due to the increasingly available non-experimental observational data and the limitations of the experimental studies, such as considerable cost, impracticality, small and less representative sample sizes, etc. In observational studies, de-confounding is a fundamental problem of individualised treatment effects (ITE) estimation. This paper proposes disentangled representations with adversarial training to selectively balance the confounders in the binary treatment setting for the ITE estimation. The adversarial training of treatment policy selectively encourages treatment-agnostic balanced representations for the confounders and helps to estimate the ITE in the observational studies via counterfactual inference. Empirical results on synthetic and real-world datasets, with varying degrees of confounding, prove that our proposed approach improves the state-of-the-art methods in achieving lower error in the ITE estimation.

Electronic Health Records (EHRs) are a valuable asset to facilitate clinical research and point of care applications; however, many challenges such as data privacy concerns impede its optimal utilization. Deep generative models, particularly, Generative Adversarial Networks (GANs) show great promise in generating synthetic EHR data by learning underlying data distributions while achieving excellent performance and addressing these challenges. This work aims to review the major developments in various applications of GANs for EHRs and provides an overview of the proposed methodologies. For this purpose, we combine perspectives from healthcare applications and machine learning techniques in terms of source datasets and the fidelity and privacy evaluation of the generated synthetic datasets. We also compile a list of the metrics and datasets used by the reviewed works, which can be utilized as benchmarks for future research in the field. We conclude by discussing challenges in GANs for EHRs development and proposing recommended practices. We hope that this work motivates novel research development directions in the intersection of healthcare and machine learning.

Federated learning (FL) is a method to train model with distributed data from numerous participants such as IoT devices. It inherently assumes a uniform capacity among participants. However, participants have diverse computational resources in practice due to different conditions such as different energy budgets or executing parallel unrelated tasks. It is necessary to reduce the computation overhead for participants with inefficient computational resources, otherwise they would be unable to finish the full training process. To address the computation heterogeneity, in this paper we propose a strategy for estimating local models without computationally intensive iterations. Based on it, we propose Computationally Customized Federated Learning (CCFL), which allows each participant to determine whether to perform conventional local training or model estimation in each round based on its current computational resources. Both theoretical analysis and exhaustive experiments indicate that CCFL has the same convergence rate as FedAvg without resource constraints. Furthermore, CCFL can be viewed of a computation-efficient extension of FedAvg that retains model performance while considerably reducing computation overhead.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Surgery is the only viable treatment for cataract patients with visual acuity (VA) impairment. Clinically, to assess the necessity of cataract surgery, accurately predicting postoperative VA before surgery by analyzing multi-view optical coherence tomography (OCT) images is crucially needed. Unfortunately, due to complicated fundus conditions, determining postoperative VA remains difficult for medical experts. Deep learning methods for this problem were developed in recent years. Although effective, these methods still face several issues, such as not efficiently exploring potential relations between multi-view OCT images, neglecting the key role of clinical prior knowledge (e.g., preoperative VA value), and using only regression-based metrics which are lacking reference. In this paper, we propose a novel Cross-token Transformer Network (CTT-Net) for postoperative VA prediction by analyzing both the multi-view OCT images and preoperative VA. To effectively fuse multi-view features of OCT images, we develop cross-token attention that could restrict redundant/unnecessary attention flow. Further, we utilize the preoperative VA value to provide more information for postoperative VA prediction and facilitate fusion between views. Moreover, we design an auxiliary classification loss to improve model performance and assess VA recovery more sufficiently, avoiding the limitation by only using the regression metrics. To evaluate CTT-Net, we build a multi-view OCT image dataset collected from our collaborative hospital. A set of extensive experiments validate the effectiveness of our model compared to existing methods in various metrics. Code is available at: https://github.com/wjh892521292/Cataract OCT.

Graphic User Interface (GUI) is facing great demand with the popularization and prosperity of mobile apps. Automatic UI code generation from UI design draft dramatically simplifies the development process. However, the nesting layer structure in the design draft affects the quality and usability of the generated code. Few existing GUI automated techniques detect and group the nested layers to improve the accessibility of generated code. In this paper, we proposed our UI Layers Group Detector as a vision-based method that automatically detects images (i.e., basic shapes and visual elements) and text layers that present the same semantic meanings. We propose two plug-in components, text fusion and box attention, that utilize text information from design drafts as a priori information for group localization. We construct a large-scale UI dataset for training and testing, and present a data augmentation approach to boost the detection performance. The experiment shows that the proposed method achieves a decent accuracy regarding layers grouping.

Communication is supposed to improve multi-agent collaboration and overall performance in cooperative Multi-agent reinforcement learning (MARL). However, such improvements are prevalently limited in practice since most existing communication schemes ignore communication overheads (e.g., communication delays). In this paper, we demonstrate that ignoring communication delays has detrimental effects on collaborations, especially in delay-sensitive tasks such as autonomous driving. To mitigate this impact, we design a delay-aware multi-agent communication model (DACOM) to adapt communication to delays. Specifically, DACOM introduces a component, TimeNet, that is responsible for adjusting the waiting time of an agent to receive messages from other agents such that the uncertainty associated with delay can be addressed. Our experiments reveal that DACOM has a non-negligible performance improvement over other mechanisms by making a better trade-off between the benefits of communication and the costs of waiting for messages.

This paper presents ReasonFormer, a unified reasoning framework for mirroring the modular and compositional reasoning process of humans in complex decision-making. Inspired by dual-process theory in cognitive science, the representation module (automatic thinking) and reasoning modules (controlled thinking) are decoupled to capture different levels of cognition. Upon the top of the representation module, the pre-trained reasoning modules are modular and professional in specific and fundamental reasoning skills (e.g., logic, simple QA, etc). To mimic the controlled compositional thinking process, different reasoning modules are dynamically activated and composed in both parallel and cascaded manners to control what reasoning skills are activated and how deep the reasoning process will be reached to solve the current problems. The unified reasoning framework solves multiple tasks with a single model, and is trained and inferred in an end-to-end manner. Evaluated on 11 datasets requiring different reasoning skills and complexity, ReasonFormer demonstrates substantial performance boosts, revealing the compositional reasoning ability. Few-shot experiments exhibit better generalization ability by learning to compose pre-trained skills for new tasks with limited data, and decoupling the representation module and the reasoning modules. Further analysis shows the modularity of reasoning modules as different tasks activate distinct reasoning skills at different reasoning depths.

给定标签噪声的数据（即数据不正确），深神经网络将逐渐记住标签噪声和损害模型性能。为了减轻此问题，提出了课程学习，以通过在有意义的（例如，易于硬）序列中订购培训样本来提高模型性能和概括。先前的工作将错误的样本作为通用的硬性样本，而无需区分硬样品（即正确数据中的硬样品）和不正确的样本。确实，模型应该从硬样本中学习，以促进概括而不是过度拟合错误。在本文中，我们通过在现有的任务损失之外附加新颖的损失函数Indimloss来解决此问题。它的主要影响是在训练的早期阶段自动，稳定地估计简易样品和困难样本（包括硬和不正确的样品）的重要性，以改善模型性能。然后，在以下阶段中，歧视专门用于区分硬性和不正确样本以改善模型的概括。这种培训策略可以以自我监督的方式动态制定，从而有效地模仿课程学习的主要原则。关于图像分类，图像回归，文本序列回归和事件关系推理的实验证明了我们方法的多功能性和有效性，尤其是在存在多样化的噪声水平的情况下。

虽然某些工作尝试从UI屏幕截图中智能生成前端代码，但在Sketch中使用UI设计草稿可能更方便，这是一种流行的UI设计软件，因为我们可以直接访问多模式UI信息，例如层，位置，位置，位置，位置，位置，，，，位置，位置，位置，，位置，位置，位置，位置，，位置，位置，位置，位置，位置，，位置，位置，位置，位置，位置，位置，位置，位置，位置，位置，位置，位置，位置，位置，位置，位置，位置类型大小和视觉图像。但是，如果所有这些层都参与了代码生成，则分散的层可能会降低代码质量，而不会合并为整个部分。在本文中，我们提出了一条管道，以自动合并碎片层。我们首先为UI草稿的图层树构造图表，并根据视觉特征和图形神经网络检测所有碎片层。然后，基于规则的算法旨在合并零碎的层。通过在新构建的数据集上的实验，我们的方法可以在UI设计草案中检索最碎片的层，并在检测任务中实现87％的准确性，并在简单且一般的情况下开发了后处理算法以聚集关联层。